Silab's driver for CP210x USB adapter can't install after Win10's latest 1803 update. Here's a workaround until they update the driver: https://www.silabs.com/community/interface/forum.topic.html/cp210x_driver_v101-91Gl
This only affects new driver installations after the 1803 upgrade. If you installed the device prior to the upgrade, you're fine.
This worked fine on a PC I just got for my office. Check out the smoking deal ($50 offer, shipped) on this monstrous refurb desktop beast with Win10 Pro: https://www.ebay.com/itm/282951085982
Good enough for most everything but gaming.